Response to Endothelial Dysfunction, Isoprostanes, and Copper Deficiency
نویسندگان
چکیده
منابع مشابه
Endothelial dysfunction, isoprostanes, and copper deficiency.
Endothelial Dysfunction, Isoprostanes, and Copper Deficiency To the Editor: Following the tradition of using animal experiments to clarify and illustrate human pathology, Lavi et al1 sought similarities between people with ischemic heart disease and animals fed cholesterol. They detected a decreased effect of acetylcholine on coronary arteries in 8 of 20 angiogram patients with minimal coronary...
متن کاملOxidative stress , F - isoprostanes and endothelial dysfunction in 2 hypercholesterolemia
See article by Wilson et al. [9] (pages 601 –607) in this attenuated by pretreatment with L-arginine or the NO issue. donor NOR-3. These observations suggest a tonic vasoconstrictor activity dynamically opposed by NO, with the net vasomotor effect resulting from the balance of the two
متن کاملPin1 deficiency causes endothelial dysfunction and hypertension.
Pin1 is a peptidyl prolyl cis-trans isomerase that only binds to and isomerizes phosphorylated serine/threonine-proline motifs, inducing conformational changes that alter target protein function and phosphorylation. We have shown previously that deficiency of another peptidyl prolyl isomerase, FK506 binding protein 12/12.6, alters endothelial NO synthase phosphorylation and causes endothelial d...
متن کاملThe roles of potassium channels in contractile response to urotensin-II in mercury chloride induced endothelial dysfunction in rat aorta
Urotensin-II (U-II), the most potent vasoconstrictor that has recently been recognized as a new candidate in cardiovascular dysfunction, might exert vasoconstriction through, at least partially, potassium channels that are predominant in both endothelial and vascular smooth muscle cells (VSMCs). The present study was designed to evaluate the roles of potassium channels in vascular responses to ...
متن کاملMagnesium deficiency and endothelial dysfunction: is oxidative stress involved?
Low magnesium (Mg) has been associated with oxidative stress, an important player in aging, atherosclerosis and other vascular diseases. In vivo, low Mg and immune system activation seem to cooperate to promote endothelial dysfunction. We therefore evaluated whether exposure of human endothelial cells to low Mg in vitro determines oxidative stress features. We therefore measured intracellular r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Hypertension
سال: 2008
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.108.116475